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hantaviruses are a family of viruses which is transmitted mainly by rodents and can show varied disease syndrome in people. The name of hantavirus varies depending on the region. In America, it is known as “New World” hantaviruses, while in Europe and Asia, it is known as “Old World” hantaviruses.
New World hantaviruses may cause hantavirus pulmonary syndrome (HPS), while Old World hantavirus may cause hemorrhagic fever with renal syndrome (HFRS).
Hantavirus was first recognized as an infectious disease in the early 1950s when a cluster of 3,000 United Nation troops stationed in Korea was struck by a mysterious illness. Ten to fifteen percent of those infected perished, [1] and though the exact etiologic agent was not discovered for two decades, it was suspected that rodents served as the main epidemiologic vector. Infection was associated with fever, hypotension, renal failure, thrombocytopenia, and disseminated intravascular coagulation (DIC). The clinical syndrome became known as hemorrhagic fever with renal syndrome (HFRS), formerly Korean hemorrhagic fever, and the virus was named Hanta after the Hantaan River of Korea. Over the ensuing years, several other etiologic agents of HFRS such as the Seoul, Puumala, and Dobrava viruses, were discovered across Europe and Asia.
In May 1993, an outbreak of an unexplained pulmonary illness occurred in the southwestern United States, in an area shared by Arizona, New Mexico, Colorado and Utah known as “The Four Corners”. A young, physically fit Navajo man suffering from shortness of breath was rushed to a hospital in New Mexico and died very rapidly. CDC
While reviewing the results of the case, medical personnel discovered that the young man’s fiancée had died a few days before after showing similar symptoms, a piece of information that proved key to discovering the disease. As Dr. James Cheek of the Indian Health Service (IHS) noted, “I think if it hadn’t been for that initial pair of people that became sick within a week of each other, we never would have discovered the illness at all”.
An investigation combing the entire Four Corners region was launched by the New Mexico Office of Medical Investigations (OMI) to find any other people who had a similar case history. Within a few hours, Dr. Bruce Tempest of IHS, working with OMI, had located five young, healthy people who had all died after acute respiratory failure.
According to CDC, There is no specific treatment, cure, or vaccine for hantavirus infection. However, we do know that if infected individuals are recognized early and receive medical care in an intensive care unit, they may do better. In intensive care, patients are intubated and given oxygen therapy to help them through the period of severe respiratory distress.
The earlier the patient is brought in to intensive care, the better. If a patient is experiencing full distress, it is less likely the treatment will be effective.
Therefore, if you have been around rodents and have symptoms of fever, deep muscle aches, and severe shortness of breath, see your doctor immediately. Be sure to tell your doctor that you have been around rodents—this will alert your physician to look closely for any rodent-carried disease, such as HPS.
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